消除对早产癌症死亡的社会经济和种族差异的影响
2011-09-18 19:45:45   来源:37度医学网   作者:  评论:0 点击:

28.26
20.48 6.85 15.28 20.22 15.29 4.42
>= 16 years of education 10.35 17.64 10.18 8.61 8.77 11.96 8.62 6.48
RR(95%CI) 4.99 (4.65 - 5.34) 4.14 (3.27 - 5.24) 5.26 (4.88 - 5.67) 1.09 (0.66 - 1.82) 3.86 (3.58 - 4.17) 2.78 (2.22 - 3.48) 4.38 (4.02 - 4.76) 0.84 (0.38 - 1.83)
绝对差异 41.28 55.37 43.31 0.79 25.09 21.24 29.09 -1.05
结直肠                
< = 12 years of education 13.59 22.45 13.18 5.34 9.75 13.97 9.74 5.11
13-15 years of education 7.41 13.46 6.74 6.30 5.65 9.87 5.23 3.26
>= 16 years of education 6.22 10.37 6.05 3.80 4.73 9.81 4.43 4.60
RR(95%CI) 2.18 (2.00 - 2.39) 2.17 (1.66 - 2.87) 2.18 (1.97 - 2.41) 1.41 (0.67 - 2.96) 2.06 (1.86 - 2.29) 1.42 (1.11 - 1.83) 2.20 (1.95 - 2.48) 1.11 (0.47 - 2.60)
绝对差异 7.37 12.08 7.13 1.54 5.02 4.16 5.31 0.51
前列腺         不适用
< = 12 years of education 3.61 9.03 3.04 1.33
13-15 years of education 2.16 5.51 1.81 1.85
>= 16 years of education 2.17 5.99 2.05 0.82
RR(95%CI) 1.66 (1.44 - 1.93) 1.51 (1.03 - 2.22) 1.48 (1.25 - 1.75) 1.61 (0.36 - 7.20)
绝对差异 1.44 3.04 0.99 0.51
Breast 不适用        
< = 12 years of education 22.12 33.53 21.41 11.93
13-15 years of education 16.23 31.17 14.60 7.97
>= 16 years of education 16.51 27.44 15.76 18.46
RR(95%CI) 1.34 (1.26 - 1.43) 1.22 (1.03 - 1.44) 1.36 (1.26 - 1.46) 0.65 (0.41 - 1.03)
绝对差异 5.60 6.09 5.64 -6.52

Figure 8 shows the numbers of potential premature cancer deaths that could have been avoided in 2007 among adults aged 25 to 64 years in the absence of socioeconomic and/or racial disparities. If everyone in the United States experienced the same overall cancer death rates as the most educated non-Hispanic whites, 37% (60,370 of 164,190) of the premature cancer deaths could potentially have been avoided. This analysis suggests that eliminating socioeconomic disparities in African Americans could potentially avert twice as many premature cancer deaths as eliminating racial disparities, underscoring the dominant role of poverty in cancer disparities.

Figure 8. Potential US* Cancer Deaths That Could Have Been Avoided by Eliminating Educational and/or Racial Disparities, Aged 25 to 64 Years, 2007.

*Excludes Rhode Island and Georgia. a Age-specific cancer death rates of the most educated non-Hispanic whites in 2007 were applied to all races.

b Age-specific cancer death rates of the most educated African Americans in 2007 were applied to all African Americans.

c Age- and educational attainment-specific cancer death rates of non-Hispanic whites in 2007 were applied to the corresponding population of African Americans.

缩略图

Cancer Survival By Race

Compared with whites, African American men and women have poorer survival once cancer is diagnosed. The 5-year relative survival is lower in African Americans than in whites for every stage of diagnosis for nearly every cancer site (Fig. 9 ). These disparities may result from inequalities in access to and receipt of quality health care and/or from differences in comorbidities. As shown in Figure 10 , African Americans are less likely than whites to be diagnosed with cancer at a localized stage, when the disease may be more easily and successfully treated. The extent to which factors other than stage at diagnosis contribute to the overall survival differential is unclear. 25 However, some studies suggest that African Americans who receive cancer treatment and medical care similar to that of whites experience similar outcomes. 26

Figure 9. Five-Year Relative Survival Rates Among Patients Diagnosed With Selected Cancers by Race and Stage at Diagnosis, United States, 1999 to 2006.

*The standard error of the survival rate is between 5 and 10 percentage points.

†The survival rate for in situ urinary bladder cancer is 97% for All Races and Whites and 94% for African Americans. Staging was performed according to Surveillance, Epidemiology, and End Results (SEER) historic stage categories rather than the American Joint Committee on Cancer (AJCC) staging system. Source: Altekruse, et al. 2

缩略图

Figure 10. Distribution of Selected Cancers by Race and Stage at Diagnosis, United States, 1999 to 2006.

*The proportion of in situ urinary bladder cancer cases is 50%, 51%, and 37% in All Races, Whites, and African Americans, respectively. Staging was performed according to Surveillance, Epidemiology, and End Results (SEER) historic stage categories rather than the American Joint Committee on Cancer (AJCC) staging system. For each cancer type, stage categories do not total 100% because sufficient information is not available to assign a stage to all cancer cases. Source: Altekruse, et al. 2

缩略图

There have been notable improvements since 1975 in the relative 5-year survival rates for many cancer sites and for all cancers combined for both whites and African Americans (Table 12 ). The improvement in survival reflects a combination of earlier diagnosis and improved treatments. Cancers for which survival has shown the least improvement over the past 30 years include lung and pancreas.

Table 12. Trends in 5-Year Relative Survival Rates * (%) by Race and Year of Diagnosis, United States, 1975 to 2006
  All Races 美国黑人
1975 to 1977 1984 to 1986 1999 to 2006 1975 to 1977 1984 to 1986 1999 to 2006 1975 to 1977 1984 to 1986 1999 to 2006
  • *

    Survival rates are adjusted for normal life expectancy and are based on cases diagnosed in the SEER 9 areas from 1975-77, 1984-86, and 1999-2006 and followed through 2007.

  • The difference in rates between 1975-1977 and 1999-2006 is statistically significant (p < 0.05).

  • The standard error of the survival rate is between 5 and 10 percentage points.

  • §

    The standard error of the survival rate is greater than 10 percentage points.

  • Survival rate is for 1978-1980.

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