科学家解开罂粟的止痛基因
2010-03-18 12:53:11 来源：丁香园 作者： 评论：0 点击：
University of Calgary researchers have found how specific genes inside the poppy plant produce the painkilling power of drugs like codeine and morphine that are derived from the flower. And by understanding how the opium poppy produces these compounds, scientists may be able to manipulate the production of opiates by genetically engineering plants or manufacturing them in a lab. This could help them produce codeine and other opiate drugs more efficiently and economically in controlled bioprocessing facilities.
卡尔加里大学的研究人员发现在罂粟植物中特定基因如何产生类似从开花植物中提取的可待因和吗啡药物的止痛效用。根据罂粟如何产生这些化合物的研究，科学家也许可以通过基因工程改良植物或在实验室生产这样的镇痛药物。这样可以帮助他们更有效和经济地控制生物加工装置以生产可待因和其他镇痛类药物。
"The enzymes encoded by these two genes have eluded plant biochemists for a half-century," says Peter Facchini, professor in the Department of Biological Sciences. "In finding not only the enzymes but also the genes, we've made a major step forward. It's equivalent [to] finding a gene involved in cancer or other genetic disorders."
“这两个基因编码的酶困惑了植物生物化学半个世纪，”生物科学系教授彼得法基尼说， “该酶和基因的发现使我们向前迈进一大步。这相当于发现了与癌症或其他遗传性疾病有关的基因。”
卡尔加里大学的研究人员发现在罂粟植物中特定基因如何产生类似从开花植物中提取的可待因和吗啡药物的止痛效用。根据罂粟如何产生这些化合物的研究，科学家也许可以通过基因工程改良植物或在实验室生产这样的镇痛药物。这样可以帮助他们更有效和经济地控制生物加工装置以生产可待因和其他镇痛类药物。
"The enzymes encoded by these two genes have eluded plant biochemists for a half-century," says Peter Facchini, professor in the Department of Biological Sciences. "In finding not only the enzymes but also the genes, we've made a major step forward. It's equivalent [to] finding a gene involved in cancer or other genetic disorders."
“这两个基因编码的酶困惑了植物生物化学半个世纪，”生物科学系教授彼得法基尼说， “该酶和基因的发现使我们向前迈进一大步。这相当于发现了与癌症或其他遗传性疾病有关的基因。”
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